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In the context of tinnitus, bioinformatic studies of synaptic transmission in spiral ganglion neurons have identified GDNF as a key protein, with proteinprotein interaction networks highlighting its role alongside BDNF in processes related to the perception of sound (Gross et al., 2023)

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Insulin, which promotes glucose uptake and utilization, can enhance the flux through the PPP, particularly in tissues like the liver and adipose tissue where lipogenesis is active

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